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Abarelix

Cat. No. M13376

All AbMole products are for research use only, cannot be used for human consumption.

Abarelix Structure
Synonym:

R3827; PPI 149

Size Price Availability Quantity
5mg USD 74 In stock
10mg USD 115 In stock
25mg USD 240 In stock
50mg USD 380 In stock
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Quality Control & Documentation
Biological Activity

Abarelix (R3827) is the first approved antagonist for the study of GnRH in advanced prostate cancer. Sequence:Ac-{d-2-Nal}-{d-4-Cpa}-{d-3-Pal}-S-{NMyr}-{d-Asp}-L-K(ipr)-P-{d-Ala}-NH2

Chemical Information
Molecular Weight 1416.06
Formula C72H95ClN14O14
CAS Number 183552-38-7
Form Solid
Solubility (25°C) DMSO : ≥ 14.2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Roger S Kirby, et al. BJU Int. Abarelix and other gonadotrophin-releasing hormone antagonists in prostate cancer

[2] Frans Debruyne, et al. Future Oncol. Abarelix for injectable suspension: first-in-class gonadotropin-releasing hormone antagonist for prostate cancer

[3] William P Hogle. Clin J Oncol Nurs. Abarelix (plenaxis)

[4] Pierre Mongiat-Artus, et al. Expert Opin Pharmacother. Abarelix: the first gonadotrophin-releasing hormone antagonist for the treatment of prostate cancer

[5] No authors listed. Drugs R D. Abarelix: abarelix-depot-F, abarelix-depot-M, abarelix-L, PPI 149, R 3827

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Keywords: Abarelix, R3827; PPI 149 supplier, LHRH/GnRH, inhibitors, activators

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