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AB-680 is a potent, reversible, selective CD73 (extracellular nucleotide enzyme) inhibitor of hCD73 Ki The value is 4.9 pM, which is more than 10,000 times more selective than the associated extracellular nucleotide CD39. Has antitumor activity.
| Molecular Weight | 580.83 |
| Formula | C20H24ClFN4O9P2 |
| CAS Number | 2105904-82-1 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 150 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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