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A2ti-1 

Cat. No. M31191

All AbMole products are for research use only, cannot be used for human consumption.

A2ti-1  Structure

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Quality Control & Documentation
Biological Activity

A2ti-1 is a selective and high-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents human papillomavirus type 16 (HPV16) infection.

Chemical Information
Molecular Weight 382.48
Formula C20H22N4O2S
CAS Number 570390-00-0
Form Solid
Solubility (25°C) DMSO >100 mg/mL (Need ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wei-Ru Huang, et al. Microbiol Spectr. Cell Entry of Avian Reovirus Modulated by Cell-Surface Annexin A2 and Adhesion G Protein-Coupled Receptor Latrophilin-2 Triggers Src and p38 MAPK Signaling Enhancing Caveolin-1- and Dynamin 2-Dependent Endocytosis

[2] Maoyang Weng, et al. J Virol. Pseudorabies Virus Regulates the Extracellular Translocation of Annexin A2 To Promote Its Proliferation

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Keywords: A2ti-1  supplier, Anti-infection, inhibitors, activators

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