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A 784168 is a potent TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin). Displays no activity against a range of receptors, including TRPA1, GABA, opioid, and purinergic receptors.
| Molecular Weight | 479.4 |
| Formula | C19H15F6N3O3S |
| CAS Number | 824982-41-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 47.94 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Caitriona O'Leary, et al. Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis
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