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A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo.
| Molecular Weight | 365.9 |
| Formula | C20H27NO3.HCl |
| CAS Number | 145307-34-2 |
| Form | Solid |
| Solubility (25°C) | Water 36.59 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] P J Blanchet, et al. Dopamine D1 receptor desensitization profile in MPTP-lesioned primates
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