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A 61603 hydrobromide

Cat. No. M6369

All AbMole products are for research use only, cannot be used for human consumption.

A 61603 hydrobromide Structure
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10mg USD 440 Custom Synthesis
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Biological Activity

A 61603 hydrobromide is a potent α-adrenoceptor agonist that is at least 35-fold more potent at α1A than at α1B or α1D sites. Induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nmol/L).

Chemical Information
Molecular Weight 390.29
Formula C14H19N3O3S.HBr
CAS Number 107756-30-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Susana Y Kamikihara, et al. alpha1-Adrenoceptors in proximal segments of tail arteries from control and reserpinised rats

[2] Clare Deighan, et al. Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice

[3] Nnaemeka Amobi, et al. Contractile actions of imidazoline alpha-adrenoceptor agonists and effects of noncompetitive alpha1-adrenoceptor antagonists in human vas deferens

[4] M A Oriowo. Functional characterization of alpha1-adrenoceptor subtypes in the rabbit spleen

[5] S M Knepper, et al. A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype

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