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A-205804

Cat. No. M2362

All AbMole products are for research use only, cannot be used for human consumption.

A-205804 Structure
Size Price Availability Quantity
5mg USD 65 In stock
10mg USD 110 In stock
25mg USD 200 In stock
50mg USD 300 In stock
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Quality Control & Documentation
Biological Activity

A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

Chemical Information
Molecular Weight 300.4
Formula C15H12N2OS2
CAS Number 251992-66-2
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gui-Dong Zhu, et al. Synthesis and mode of action of (125)I- and (3)H-labeled thieno[2,3-c]pyridine antagonists of cell adhesion molecule expression

[2] G D Zhu, et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides

[3] A O Stewart, et al. Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression

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Keywords: A-205804 supplier, Integrin, inhibitors, activators

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