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8-Aminoadenine is a adenine receptor agonist (Ki = 0.0341 μM in HEK293 cells expressing an adenine binding site). Displays 190-fold increased potency at the human binding site over the rat adenine receptor (rAde1R) (Ki = 6.51 μM).
| Molecular Weight | 150.14 |
| Formula | C5H6N6 |
| CAS Number | 28128-33-8 |
| Solubility (25°C) | DMSO 7.51 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Anna Avi, et al. Structural properties of g,t-parallel duplexes
[4] Miriam Frieden, et al. Convenient synthesis of 8-amino-2'-deoxyadenosine
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