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Methylnissolin (Astrapterocarpan) inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase.
| Molecular Weight | 300.31 |
| Formula | C17H16O5 |
| CAS Number | 73340-41-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | 4°C, protect from light |
| Related VEGFR/PDGFR Products |
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| Axitinib
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| Nintedanib
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