Free shipping on all orders over $ 500

7-Epitaxol

Cat. No. M4417

All AbMole products are for research use only, cannot be used for human consumption.

7-Epitaxol Structure
Synonym:

7-epi-Paclitaxel

Size Price Availability Quantity
5mg USD 55 In stock
10mg USD 90 In stock
20mg USD 140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

7-Epi-Taxol is the active metabolite of Taxol, which has similar effects to Taxol in inhibiting cell proliferation, microtubule dissociation and inducing microtubule polymerization.

Chemical Information
Molecular Weight 853.91
Formula C47H51NO14
CAS Number 105454-04-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] V Bharath Kumar, et al. 7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway

[2] Yanjie Liu, et al. An effective method to produce 7-epitaxol from taxol in HCO 3

[3] Jianhua Li, et al. Microbial transformation of cephalomannine by Luteibacter sp

[4] I Royer, et al. Paclitaxel metabolites in human plasma and urine: identification of 6 alpha-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry

[5] I Ringel, et al. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium

Related Microtubule Products
ABT-751

ABT-751 is an orally bioavailable tubulin inhibitor with IC50 of about 1.5 and 3.4 µM in neuroblastoma and non-neuroblastoma cell lines, respectively.

Vincristine sulfate

Vincristine, formally known as leurocristine, is a mitotic inhibitor used in cancer chemotherapy.

Docetaxel

Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity.

Paclitaxel

Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM.

Fosbretabulin disodium

Fosbretabulin disodium (Combretastatin A-4 phosphate) is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: 7-Epitaxol, 7-epi-Paclitaxel supplier, Microtubule, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.