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7-Chlorokynurenic acid sodium salt

Cat. No. M6355

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7-Chlorokynurenic acid sodium salt Structure
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10mg USD 70 4-7 Days
50mg USD 280 4-7 Days
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Biological Activity

7-Chlorokynurenic acid sodium salt is a sodium salt of 7-Chlorokynurenic acid, an NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles.

Chemical Information
Molecular Weight 245.59
Formula C10H5ClNNaO3
CAS Number 1263094-00-3
Form Solid
Solubility (25°C) Water 24.56 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R A Wallis, et al. Glycine-induced CA1 excitotoxicity in the rat hippocampal slice

[2] R A Wallis, et al. Glycine-induced CA1 excitotoxicity in the rat hippocampal slice

[3] J J Woodward, et al. Potentiation of N-methyl-D-aspartate-stimulated dopamine release from rat brain slices by aluminum fluoride and carbachol

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