All AbMole products are for research use only, cannot be used for human consumption.
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.
| Molecular Weight | 418.65 |
| Formula | C27H46O3 |
| CAS Number | 64907-22-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 4.55 mg/mL (ultrasonic) Ethanol 1 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[3] William J Griffiths, et al. J Lipid Res. Cholesterol metabolism: from lipidomics to immunology
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