Free shipping on all orders over $ 500

6-Thio-2′-Deoxyguanosine

Cat. No. M8490

All AbMole products are for research use only, cannot be used for human consumption.

6-Thio-2′-Deoxyguanosine Structure
Synonym:

6-thio-dG; β-TGdR

Size Price Availability Quantity
5mg USD 70 In stock
10mg USD 100 In stock
25mg USD 220 In stock
50mg USD 360 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.

Chemical Information
Molecular Weight 283.31
Formula C10H13N5O3S
CAS Number 789-61-7
Solubility (25°C) DMSO: ≥ 30 mg/mL
Storage 4°C, protect from light
References

[1] Mender I, et al. Cancer Discov. Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.

Related DNA/RNA Synthesis Products
Clofarabine

Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Gemcitabine Hydrochloride

Gemcitabine (Gemzar, LY188011) inhibits DNA synthesis with an IC50 of 0.06 µM.

Nelarabine

Nelarabine is a novel purine antimetabolite antineoplastic agent.

Mizoribine

Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM. Mizoribine inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively.

Capecitabine

Capecitabine is an orally-administered chemotherapeutic agent. Capecitabine is a precursor, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. Capecitabine may inhibit cytochrome CYP2C9 enzyme, and therefore increase levels of substrates such as phenytoin and other substrates of CYP2C9.

  Catalog
Abmole Inhibitor Catalog




Keywords: 6-Thio-2′-Deoxyguanosine, 6-thio-dG; β-TGdR supplier, DNA/RNA Synthesis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.