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5-NIdR

Cat. No. M41282

All AbMole products are for research use only, cannot be used for human consumption.

5-NIdR Structure

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Quality Control & Documentation
Biological Activity

5-NIdR (1-(β-D-2-Deoxyribofuranosyl)-5-nitroindole), an artificial nucleoside, exhibits the ability to inhibit the replication of DNA lesions generated by Temozolomide.

Chemical Information
Molecular Weight 278.26
Formula C13H14N2O5
CAS Number 191421-10-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jung-Suk Choi et al. Cancer Res. Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer

[2] Md Faiz Ahmad et al. Mol Cancer Ther. Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase

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Keywords: 5-NIdR supplier, Apoptosis, inhibitors, activators

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