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5-Hydroxyindole

Cat. No. M9830

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5-Hydroxyindole Structure
Synonym:

1H-indole-5-ol

Size Price Availability Quantity
1g USD 55 In stock
5g USD 195 In stock
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Quality Control & Documentation
Biological Activity

5-Hydroxyindole is a reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl) benzenesulfonates as antitumor agents and tubulin inhibitors. Reactant for preparation of anthranilic acids. Reactant for preparation of indole compounds as dopamine D2 receptor antagonists. Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands. Reactant for preparation of melanins as nature-inspired radioprotectors. Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors.

Chemical Information
Molecular Weight 133.15
Formula C8H7NO
CAS Number 1953-54-4
Form Solid
Storage 2-8°C, protect from light, dry, sealed
References

[1] Ruth Livingstone, et al. J Chem Phys. Following the excited state relaxation dynamics of indole and 5-hydroxyindole using time-resolved photoelectron spectroscopy

[2] Dimitrios Andreou, et al. Psychiatry Res. Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: 5-Hydroxyindole, 1H-indole-5-ol supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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