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5-Fluorouridine is a metabolite of 5-fluorouracil, a potent inhibitor of nuclease autocleavage. 5-Fluorouridine binds to total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis (cell death).
| Molecular Weight | 262.19 |
| Formula | C9H11FN2O6 |
| CAS Number | 316-46-1 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related DNA/RNA Synthesis Products |
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| Nelarabine
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| Capecitabine
Capecitabine is an orally-administered chemotherapeutic agent. Capecitabine is a precursor, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. Capecitabine may inhibit cytochrome CYP2C9 enzyme, and therefore increase levels of substrates such as phenytoin and other substrates of CYP2C9. |
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