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5-Carboxamidotryptamine

Cat. No. M30571

All AbMole products are for research use only, cannot be used for human consumption.

5-Carboxamidotryptamine Structure
Synonym:

5-CT

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Quality Control & Documentation
Biological Activity

5-Carboxamidotryptamine (5-CT) is a 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, 5-HT7 receptor agonist. 5-Carboxamidotryptamine has a Ki value of 4.6 nM for cloned human 5-HT5A receptor. 5-Carboxamidotryptamine causes a dose-dependent reduction in rectal temperature of mice.

Chemical Information
Molecular Weight 203.24
Formula C11H13N3O
CAS Number 74885-09-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Cathérine Delesalle, et al. Br J Pharmacol. Contractile effects of 5-hydroxytryptamine and 5-carboxamidotryptamine in the equine jejunum

[2] D L Nelson. Curr Drug Targets CNS Neurol Disord. 5-HT5 receptors

[3] J M Palacios, et al. Behav Brain Res. Autoradiographic analysis of 5-HT receptor subtypes labeled by [3H]5-CT ([3H]5-carboxamidotryptamine)

[4] M S Beer, et al. Eur J Pharmacol. 5-Carboxamidotryptamine-insensitive 5-HT1-like receptors are concentrated in guinea pig but not rat, claustrum

[5] K J Simansky. Pharmacol Biochem Behav. Peripheral 5-carboxamidotryptamine (5-CT) elicits drinking by stimulating 5-HT1-like serotonergic receptors in rats

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Keywords: 5-Carboxamidotryptamine, 5-CT supplier, 5-HT Receptor, inhibitors, activators

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