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5-BDBD is a potent P2X4 receptor antagonist. Blocks P2X4-mediated currents in Chinese hamster ovary cells (IC50 = 0.50 μM). 5-BDBD exhibits no significant antagonist effects at other P2X receptors. 5-BDBD reduces long-term potentiation (LTP) in rat hippocampal slices.
| Molecular Weight | 355.19 |
| Formula | C17H11BrN2O2 |
| CAS Number | 768404-03-1 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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