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5,6-Dichlorobenzimidazole riboside

Cat. No. M31193

All AbMole products are for research use only, cannot be used for human consumption.

5,6-Dichlorobenzimidazole riboside Structure
Synonym:

DRB

Size Price Availability Quantity
5mg USD 30 In stock
10mg USD 45 In stock
25mg USD 90 In stock
50mg USD 135 In stock
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Quality Control & Documentation
Biological Activity

5,6-Dichlorobenzimidazole riboside is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs. 5,6-Dichlorobenzimidazole riboside trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells.

Chemical Information
Molecular Weight 319.14
Formula C12H12Cl2N2O4
CAS Number 53-85-0
Form Solid
Solubility (25°C) DMSO 90 mg/mL (Need ultrasonic)
DMF 90 mg/mL (Need ultrasonic)
Storage Powder -20°C
References

[1] Odile Bartholomé, et al. J Struct Biol. Relationships between the structural and functional organization of the turtle cell nucleolus

[2] Jin-Young Yoon, et al. Am J Physiol Cell Physiol. Modulation of nicotinic receptor channels by adrenergic stimulation in rat pinealocytes

[3] Hao-Yen Chang, et al. Cancer Res. hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress

[4] R Zou, et al. Nucleosides Nucleotides Nucleic Acids. Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections

[5] S Aké, et al. Biochimie. 5,6-Dichlorobenzimidazole-1-beta-D-riboside, specific inhibitor of cytokinin activity in tobacco cell suspension cultures

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Keywords: 5,6-Dichlorobenzimidazole riboside, DRB supplier, CDK, inhibitors, activators

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