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4'-Hydroxychalcone

Cat. No. M20439

All AbMole products are for research use only, cannot be used for human consumption.

4'-Hydroxychalcone Structure
Synonym:

P-Cinnamoylphenol

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Quality Control & Documentation
Biological Activity

4'-Hydroxychalcone, found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manner and activating BMP signaling.

Chemical Information
Molecular Weight 224.25
Formula C15H12O2
CAS Number 2657-25-2
Solubility (25°C) DMSO 44 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Selene de Jess Acosta-Cota, et al. Can J Physiol Pharmacol. Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury

[2] Carmlia I Lobo, et al. ACS Omega. Topical Application of 4'-Hydroxychalcone in Combination with tt- Farnesol Is Effective against Candida albicans and Streptococcus mutans Biofilms

[3] Qing Chen, et al. Oncol Lett. Erratum: Chemopreventive effect of 4'-hydroxychalcone on intestinal tumorigenesis in ApcMin mice

[4] Qing Chen, et al. Oncol Lett. Chemopreventive effect of 4'-hydroxychalcone on intestinal tumorigenesis in ApcMin mice

[5] Amnah M Alshangiti, et al. Oxid Med Cell Longev. 4-Hydroxychalcone Induces Cell Death via Oxidative Stress in MYCN-Amplified Human Neuroblastoma Cells

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Keywords: 4'-Hydroxychalcone, P-Cinnamoylphenol supplier, inhibitors, activators

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