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4-Acetyl-1,1-dimethylpiperazinium iodide

Cat. No. M6341

All AbMole products are for research use only, cannot be used for human consumption.

4-Acetyl-1,1-dimethylpiperazinium iodide Structure
Size Price Availability
10mg USD 275 Custom Synthesis
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Quality Control & Documentation
Biological Activity

4-Acetyl-1,1-dimethylpiperazinium iodide is a structural analog of acetylcholine that acts as a nicotinic agonist (Ki = 29.9 nM at α4β2). Upregulates the number of α4β2 binding sites in M10 cells in vitro by 440%.

Chemical Information
Molecular Weight 284.14
Formula C8H17IN2O
CAS Number 75667-84-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Daneli Lpez Prez, et al. Experimental and statistical methods to evaluate antibacterial activity of a quaternary pyridinium salt on planktonic, biofilm-forming, and biofilm states

[2] C E Spivak, et al. Structural and electronic requirements for potent agonists at a nicotinic receptor

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Keywords: 4-Acetyl-1,1-dimethylpiperazinium iodide supplier, AChR/AChE, inhibitors, activators

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