All AbMole products are for research use only, cannot be used for human consumption.
3-Nitropropionic acid is a irreversible mitochondrial respiratory complex II (succinate dehydrogenase) inhibitor; induces autophagy in SH-SY5Y cells. Recapitulates Huntington's disease-like pathology and symptoms in primate and rodent models.
| Molecular Weight | 119.08 |
| Formula | C3H5NO4 |
| CAS Number | 504-88-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 11.91 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Thomas Birkelund, et al. Fatal 3-Nitropropionic Acid Poisoning after Consuming Coconut Water
[5] C V Borlongan, et al. 3-Nitropropionic acid animal model and Huntington's disease
| Related Animal Modeling Products |
|---|
| Doxorubicin HCL
Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| Streptozotocin
Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| Bleomycin sulfate
Bleomycin sulfate (Blenoxane) is a glycopeptide antitumor antibiotic isolated from Streptomyces verticillus. |
| Loperamide hydrochloride
Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively. Loperamide hydrochloride is also a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. It can be used to construct animal models of functional constipation. |
| Imiquimod
Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
