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3',​4',​5',​5,​7-​Pentamethoxyflavone

Cat. No. M13450

All AbMole products are for research use only, cannot be used for human consumption.

3',​4',​5',​5,​7-​Pentamethoxyflavone  Structure
Size Price Availability Quantity
5mg USD 150 In stock
10mg USD 250 In stock
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Quality Control & Documentation
Biological Activity

3',4',5',5, 7-pentamethoxyflavone is a natural brass compound extracted from Rutaceae. 3',4',5',5,7-Pentamethoxyflavone could be used as an effective adjuvant sensitizer to increase the efficacy of chemotherapeutic compounds by downregulating Nrf2 signaling pathway, it sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway.

Chemical Information
Molecular Weight 372.37
Formula C20H20O7
CAS Number 53350-26-8
Form Solid
Solubility (25°C) Hot Acetone
Warm Ethanol
Methanol
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jordano Augusto Carvalho Sousa, et al. Nat Prod Res. New flavone, and cytotoxicity activity of Rauia resinosa ethanolic extract and constituents

[2] Qiang You, et al. J Agric Food Chem. Pharmacokinetics and Metabolites of 12 Bioactive Polymethoxyflavones in Rat Plasma

[3] Mateusz Łużny, et al. J Agric Food Chem. Biotransformation of 5,7-Methoxyflavones by Selected Entomopathogenic Filamentous Fungi

[4] Yuqin Zhang, et al. Evid Based Complement Alternat Med. Apoptosis Effects of Dihydrokaempferol Isolated from Bauhinia championii on Synoviocytes

[5] Yang-Jing Luo, et al. Zhong Yao Cai. [Study on chemical constituents of Gardenia jasminoides(III)]

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Keywords: 3',​4',​5',​5,​7-​Pentamethoxyflavone supplier, inhibitors, activators

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