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3-(2,4-Dihydroxyphenyl)propanoic acid (DPPacid) is a potent and competitive tyrosinase inhibitor, inhibits L-Tyrosine and DL-DOPA with an IC50 and a Ki of 3.02 μM and 11.5 μM, respectively.
| Molecular Weight | 182.17 |
| Formula | C9H10O4 |
| CAS Number | 5631-68-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 150 mg/mL (ultrasonic) |
| Storage | 4°C, sealed |
| Related Tyrosinase Products |
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| Deoxyarbutin
Deoxyarbutin can effectively inhibit tyrosinase activity and melanin synthesis, and obtain significant and lasting whitening effect, with strong antioxidant effect. |
| α-Methyl-p-tyrosine
α-Methyl-p-tyrosine (AMPT) is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. α-Methyl-p-tyrosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. |
| Trifolirhizin
Trifolirhizin is a pterocarpan flavonoid isolated from the root of Sophora flavescoreae. Trifolirhizin showed high tyrosinase inhibitory activity with IC50 of 506 μM. Trifolirhizin has potential anti-inflammatory and anticancer activities. |
| XMD8-87
XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations. |
| XMD16-5
XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations. |
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