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24-Norursodeoxycholic acid

Cat. No. M21462

All AbMole products are for research use only, cannot be used for human consumption.

24-Norursodeoxycholic acid  Structure
Synonym:

nor-UDCA

Size Price Availability Quantity
5mg USD 65 In stock
10mg USD 100 In stock
25mg USD 160 In stock
50mg USD 255 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties.

Chemical Information
Molecular Weight 378.55
Formula C23H38O4
CAS Number 99697-24-2
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alix Bruneau, et al. Curr Opin Gastroenterol. Macrophages in cholangiopathies

[2] Ci Zhu, et al. J Hepatol. 24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation

[3] Maria Reich, et al. J Hepatol. Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

[4] Peter Fickert, et al. Gastroenterology. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

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Keywords: 24-Norursodeoxycholic acid , nor-UDCA supplier, inhibitors, activators

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