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20(S)-Protopanaxatriol

Cat. No. M3883

All AbMole products are for research use only, cannot be used for human consumption.

20(S)-Protopanaxatriol Structure
Synonym:

g-PPT

Size Price Availability Quantity
5mg USD 60 In stock
10mg USD 90 In stock
50mg USD 250 In stock
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Quality Control & Documentation
Biological Activity

20(S)-Protopanaxatriol enhanced adipogenesis by increasing the expression of PPARgamma target genes such as aP2, LPL and PEPCK. Furthermore, 20(S)-Protopanaxatriol significantly increased expression of glucose transporter 4 (GLUT4).20(S)-Protopanaxatriol can be developed as a PPARgamma agonist for the improvement of insulin resistance associated with diabetes.PPD and PPT may exhibit the anxiolytic effect via γ-aminobutyrateA (GABAA) receptor(s) and serotonergic receptor(s), respectively.

Chemical Information
Molecular Weight 476.73
Formula C30H52O4
CAS Number 34080-08-5
Form Solid
Solubility (25°C) DMSO 47mg/ml
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Oh HA, et al. Biol Pharm Bull. Anti-stress effects of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol in immobilized mice.

[2] He C, et al. J Pharm Biomed Anal. Identification of 20(S)-protopanaxatriol metabolites in rats by ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry and nuclear magnetic resonance spectroscopy.

[3] Han KL, et al. Biol Pharm Bull. Ginsenoside 20S-protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes.

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Keywords: 20(S)-Protopanaxatriol, g-PPT supplier, GCR, inhibitors, activators

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