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2-Methoxyestrone

Cat. No. M14345

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2-Methoxyestrone Structure
Size Price Availability Quantity
1mg USD 60 In stock
5mg USD 150 In stock
10mg USD 240 In stock
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Quality Control & Documentation
Biological Activity

2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.

Chemical Information
Molecular Weight 300.39
CAS Number 362-08-3
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R HOBKIRK, et al. 2-methoxyestrone as an estrogen metabolite in the human subject

[2] A Singh, et al. Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate

[3] C Longcope, et al. Metabolism of 2-methoxyestrone in normal men

[4] C P Martucci. The role of 2-methoxyestrone in estrogen action

[5] P Ball, et al. Radioimmunoassay of 2-hydroxyesterone and 2-methoxyestrone in human urine

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: 2-Methoxyestrone supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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