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2-(4-Methylpiperazin-1-yl)pyrimidine

Cat. No. M9662

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2-(4-Methylpiperazin-1-yl)pyrimidine Structure
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Biological Activity

2-(4-Methylpiperazin-1-yl)pyrimidine

Chemical Information
Molecular Weight 178.23
Formula C9H14N4
CAS Number 145208-86-2
Storage 2-8°C, dry, protect from light, sealed
References

[1] Jianhang Huang, et al. Discovery of N-(4-(3-isopropyl-2-methyl-2 H-indazol-5-yl)pyrimidin-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-7-amine as a Novel, Potent, and Oral Cyclin-Dependent Kinase Inhibitor against Haematological Malignancies

[2] Xiaoyang Li, et al. Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant

[3] Meng-Zhen Lai, et al. Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors

[4] Mengting Han, et al. 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)phenyl)pyrimidine-2,4-diamine (WY-135), a novel ALK inhibitor, induces cell cycle arrest and apoptosis through inhibiting ALK and its downs䲧畸Ỵ畹㧀畷羹皖睑긘एŤए �皘

[5] Xiaohong Wang, et al. Synthesis of N-(3-(4-[ 11 C]methylpiperazin-1-yl)-1-(5-methylpyridin-2-yl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide as a new potential PET agent for imaging of IRAK4 enzyme in neuroinflammation

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Keywords: 2-(4-Methylpiperazin-1-yl)pyrimidine supplier, inhibitors, activators

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