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1NM-PP1

Cat. No. M9798

All AbMole products are for research use only, cannot be used for human consumption.

1NM-PP1 Structure
Synonym:

1-NM-PP1; PP1 Analog II

Size Price Availability Quantity
1mg USD 50 In stock
5mg USD 125 In stock
10mg USD 195 In stock
25mg USD 375 In stock
50mg USD 760 In stock
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Quality Control & Documentation
Biological Activity

1NM-PP1 is a cell-permeable and potent Src family kinases inhibitor with IC50 values of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively.

Chemical Information
Molecular Weight 331.41
Formula C20H21N5
CAS Number 221244-14-0
Solubility (25°C) DMSO ≥ 17 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tatsuki Sugi, et al. J Vet Med Sci. 1NM-PP1 treatment of mice infected with Toxoplasma gondii

[2] Tatsuki Sugi, et al. Eukaryot Cell. Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step

[3] Stephane Larochelle, et al. Mol Cell. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells

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Keywords: 1NM-PP1, 1-NM-PP1; PP1 Analog II supplier, Src-bcr-Abl, inhibitors, activators

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