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123B9 is a tumor-homing agent, it is also a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain.
| Molecular Weight | 1321.79 |
| Formula | C58H82ClFN12O20 |
| CAS Number | 2225868-19-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Ephrin Receptor Products |
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| ALW-II-41-27
ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor with an IC50 of 11 nM for EPHA2. |
| NVP-BHG712 isomer
NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4. |
| ALW-II-49-7
ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell. |
| 123C4
123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4, with a Ki value of 0.65 μM. |
| Urolithin D
Urolithin D is competitive and reversible antagonist of EphA receptors. |
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