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11-​Keto-​beta-​boswellic acid

Cat. No. M11119

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11-​Keto-​beta-​boswellic acid Structure
Synonym:

11-Keto-β-boswellic acid

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5mg USD 160 In stock
10mg USD 260 In stock
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Biological Activity

11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenoid acid derived from the oleoresin of the bark of the Boswellia serrate tree commonly known as Indian Frankincense. 11-Keto-beta-boswellic acid has anti-inflammatory activity, mainly due to inhibition of 5-lipoxygenase (5-lipoxygenase; Activation of 5-LOX), leukotriene, activation of NF-κB and production of tumor necrosis factor α.

Chemical Information
Molecular Weight 470.68
Formula C30H46O4
CAS Number 17019-92-0
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Cheng Wei Lu, et al. Planta Med. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus

[2] Thomas Efferth, et al. Semin Cancer Biol. Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities

[3] Muhammed Majeed, et al. Phytother Res. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee

[4] Daniela Catanzaro, et al. PLoS One. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage

[5] M Z Siddiqui. Indian J Pharm Sci. Boswellia serrata, a potential antiinflammatory agent: an overview

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Keywords: 11-​Keto-​beta-​boswellic acid, 11-Keto-β-boswellic acid supplier, Lipoxygenase, inhibitors, activators

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