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CHF5407 

Cat. No. M27607

All AbMole products are for research use only, cannot be used for human consumption.

CHF5407  Structure

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Quality Control & Documentation
Biological Activity

CHF5407 is a selective, long-acting and competitive muscarinic M3 receptor antagonist. CHF5407 shows subnanomolar affinities for human muscarinic M1 (hM1), M2 (hM2) and M3 (hM3) receptors. CHF5407 shows a prolonged antibronchospastic activity.

Chemical Information
Molecular Weight 613.46
Formula C27H25BrF4N2O3S
CAS Number 1004312-94-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Mario Cazzola, et al. Pulm Pharmacol Ther. Long-acting muscarinic receptor antagonists for the treatment of respiratory disease

[2] G Villetti, et al. J Pharmacol Exp Ther. Bronchodilator activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a potent, long-acting, and selective muscarinic M3 receptor antagonist

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  Catalog
Abmole Inhibitor Catalog




Keywords: CHF5407  supplier, AChR/AChE, inhibitors, activators

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