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1,2,3,4,6-pentagalloylglucose

Cat. No. M4757

All AbMole products are for research use only, cannot be used for human consumption.

1,2,3,4,6-pentagalloylglucose Structure
Synonym:

Pentagalloylglucose; Penta-O-galloyl-β-D-glucose

Size Price Availability Quantity
1mg USD 30 In stock
5mg USD 60 In stock
10mg USD 85 In stock
20mg USD 125 In stock
50mg USD 240 In stock
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Biological Activity

1,2,3,4,6-pentagalloylglucose (Pentagalloylglucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities.

Chemical Information
Molecular Weight 940.68
Formula C41H32O26
CAS Number 14937-32-7
Form Solid
Solubility (25°C) DMSO 70 mg/mL
Water 4 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tomasz P Mikolajczyk, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension

[2] Sang Hee Kawk, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose suppresses colon cancer through induction of tumor suppressor

[3] Kun Chun, et al. Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain

[4] Yoon Hee Kim, et al. 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice

[5] J Cammann, et al. Biosynthesis of gallotannins: beta-glucogallin-dependent formation of 1,2,3,4,6-pentagalloylglucose by enzymatic galloylation of 1,2,3,6-tetragalloylglucose

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Keywords: 1,2,3,4,6-pentagalloylglucose, Pentagalloylglucose; Penta-O-galloyl-β-D-glucose supplier, Apoptosis, inhibitors, activators

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