| Cat.No. | Name | Information |
|---|---|---|
| M10459 | MSA-2 | MSA-2 is an orally available non-nucleotide STING agonist with antitumor activity. MSA-2 shows EC50 values of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. |
| M9923 | SR-717 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. |
| M9893 | C-176 | C-176 is a potent, selective and blood-brain barrier permeable inhibitor of STING. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING. |
| M10126 | H-151 | H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation. |
| M40556 | IMSA101 | IMSA101 is a STING1 agonist that can be used in studies related to solid tumors. |
| M40555 | BI1387446 | BI1387446 is a STING1 agonist that can be used in studies related to solid tumors. |
| M40554 | SB11285 | SB11285 is a STING1 stimulator that can be used in melanoma related studies. |
| M29813 | PROTAC STING Degrader-1 | PROTAC STING Degrader-1 (Compound SP23) is a STING PROTAC degrader with a DC50 of 3.2 μM. PROTAC STING Degrader-1 shwos anti-inflammatory activity. |
| M29779 | BSP16 | BSP16 is a potent, orally active stimulator of interferon genes (STING) agonist. BSP16 can selectively stimulate the STING pathway. BSP16 can be used for the research of cancer. |
| M29704 | Dazostinag disodium | Dazostinag disodium (TAK-676) is an agonist of STING, triggering the activation of STING signaling pathway and type I interferons. Dazostinag disodium is also a modulator of immune system, resulting complete regressions and durable memory T-cell immunity. Dazostinag disodium promotes durable IFN-dependent antitumor immunity. |
| M29703 | Dazostinag | Dazostinag (TAK-676 free base) is an agonist of stimulator of interferon genes (STING) protein with antineoplastic activity. Dazostinag can serve as a playload to synthesis antibody-drug conjugates (ADCs). |
| M29556 | SR-717 free acid | SR-717 free acid is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity. |
| M29463 | STING agonist-12 | STING agonist-12 (Compound 53) is a potent, orally active human STING activator with an EC50 of 185 nM. |
| M29290 | STING agonist-4 | STING agonist-4 is an stimulator of Interferon Genes (STING) receptor agonist with an apparent inhibitory constant (IC50) of 20 nM. STING agonist-4 is a two symmetry-related amidobenzimidazole (ABZI)-based compound to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function. |
| M21074 | Ulevostinag | Ulevostinag (MK-1454 ) is an intratumoral stimulator (STING) agonist of the interferon (IFN) gene that is being developed for the study of advanced solid tumors and lymphomas. |
| M14122 | Cyclic-di-GMP diammonium | Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species. |
| M10766 | ADU-S100 disodium salt | ADU-S100 disodium salt (MIW815 disodium salt) is an activator (STING) of interferon gene stimulators with potent antitumor and immune activity. |
| M10765 | ADU-S100 ammonium salt | ADU-S100 ammonium salt (MIW815 ammonium salt) is an activator (STING) of interferon gene stimulators with potent antitumor and immune activity. |
| M9084 | ADU-S100 | ADU-S100 (MIW815; ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes). |
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