| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M58140 | HwTx-IV | Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule. |
| M42248 | ProTx II TFA | ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. |
| M5069 | S0859 | S0859 is an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). |
| M5897 | Prilocaine | Prilocaine is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. |
| M49397 | ATX-II TFA | ATX-II TFA, a specific Na+ channel modulator toxin derived from sea anemone (Anemonia sulcata) venom, causes sensitization of cell cultures to Na+Halothane , Caffeine, and Ryanodine. In addition, ATX-II induces pulmonary venous arrhythmias and atrial fibrillation. |
| M42258 | Aah II | Aah II is a sodium channel modulator. |
| M42257 | Ancistrotecine B | Ancistrotecine B is a Nav1.7 channel inhibitor (IC50: 0.73 μM). |
| M42256 | Hm1a | Hm1a is a disulfide-rich spider-venom peptide, and a NaV1.1 activator. |
| M42255 | Aneratrigine | Aneratrigine is a sodium channel protein type 9 subunit alpha blocker. |
| M42254 | Dc1a | Dc1a potently promotes opening of the German cockroach Nav channel (BgNav1). |
| M42253 | Aneratrigine hydrochloride | Aneratrigine (hydrochloride) is a sodium channel protein type 9 subunit alpha blocker. |
| M42252 | 6-Iodoamiloride | 6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. |
| M42251 | DS43260857 | DS43260857 is a potentNaV1.7inhibitor, which has a high inhibitory effect on both human and mouse NaV1.7. |
| M42250 | Nav1.3 channel inhibitor 1 | Nav1.3 channel inhibitor 1 is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). |
| M42249 | ATX-II | ATX-II is a specific Na+ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). |
| M40702 | PF-04531083 | PF-04531083 is a selective NaV1.8 blocker for studies related to chronic pain. |
| M39045 | Cyfluthrin | Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product. |
| M39042 | 6-Benzoylheteratisine | 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine. |
| M31237 | Idrevloride | Idrevloride is an epithelial sodium channel (ENaC) inhibitor, can be used for the research of skin disorders. |
| M31053 | QAQ dichloride | QAQ dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain. |
| M30982 | DPI 201-106 | DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect. |
| M30875 | XEN907 | XEN907 is a potent and spirooxindole blocker of NaV1.7, with an IC50 of 3 nM. XEN907 also inhibits CYP3A4 in a recombinant human enzyme assay. XEN907 can be used for the research of pain. |
| M30797 | Pilsicainide | Pilsicainide (SUN 1165 free acid) is a potent sodium channel blocker and potent class Ic antiarrhythmic agent. |
| M30796 | Pilsicainide hydrochloride | Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent. |
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