| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M58140 | HwTx-IV | Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule. |
| M42248 | ProTx II TFA | ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. |
| M5069 | S0859 | S0859 is an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). |
| M5897 | Prilocaine | Prilocaine is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. |
| M52719 | β-Pompilidotoxin | β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells. |
| M52718 | µ-Conotoxin-CnIIIC | μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. |
| M52717 | µ-Conotoxin KIIIA | μ-Conotoxin KIIIA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. |
| M52716 | µ-Conotoxin SIIIA | μ-Conotoxin SIIIA is a tetrodotoxin (TTX)-resistant sodium channel blocker. |
| M52715 | ω-Conotoxin CVIB | ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. |
| M52714 | μ-Conotoxin PIIIA | μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. |
| M52713 | µ-Conotoxin GIIIB | μ-Conotoxin GIIIB is a 22-residue polypeptide that can be isolated from the venom of piscivorous cone snail Conus geographus. |
| M52712 | µ-Conotoxin BuIIIC | μ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) is a potent Nav1.4 inhibitor. |
| M52711 | µ-Conotoxin BuIIIB | μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB) is a mammalian neuronal voltage-gated sodium channel (VGSC) blocker. |
| M52710 | μ-Conotoxin Sx IIIA | μ-Conotoxin Sx IIIA is a biological active peptide. |
| M52709 | Hainantoxin-III | Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC50 value of 604.2 nM. |
| M52708 | Hainantoxin-IV | Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. |
| M52707 | Ceratotoxin-2 | Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. |
| M52706 | Mambalgin 1 | Mambalgin-1 is a toxin isolated from black mamba venom. |
| M52705 | GpTx-1 | GpTx-1 is a potent and selective NaV1.7 antagonist with an IC50 of 10 nM. |
| M49943 | PF-06305591 dihydrate | PF-06305591 dihydrate is a potent, highly selective blocker of the voltage-gated sodium channel NaV1.8 with an IC50 value of 15 nM for pain-related studies. |
| M49942 | PF-06305591 | PF-06305591 is a potent and highly selective blocker of the voltage-gated sodium channel NaV1.8 with an IC50 value of 15 nM for pain-related studies. |
| M49941 | VX-128 | VX-128 is a Nav1.8 blocker that can be used in studies related to acute pain. |
| M49823 | PRAX-628 | PRAX-628 is a potential best-in-class, selective small molecule inhibitor of sodium channels that targets sodium channels in the brain in a hyperexcitable state. It can be used in studies related to focal epilepsy. |
| M49486 | BI 1265162 | BI 1265162 is a selective epithelial sodium channel (ENaC) inhibitor for studies related to cystic fibrosis (CF). |
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