| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M3006 | Sertraline hydrochloride | Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM. |
| M7684 | Clozapine N-oxide | Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC. |
| M59061 | PF-03382792 | PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. |
| M3772 | SB242084 | SB242084 has a high affinity (pKi 9.0) for the cloned human 5-HT2C receptor and 100- and 158-fold selectivity over the closely related cloned human 5-HT2B and 5-HT2A subtypes respectively. |
| M6946 | Melperone hydrochloride | Melperone hydrochloride is a 5-HT2A/D2 receptor antagonist; neuroleptic. |
| M6933 | LY334370 | LY 334370 is a selective 5-HT1F agonist. |
| M6760 | GR 127935 hydrochloride | GR 127935 hydrochloride is a potent, selective 5-HT 1B/1D antagonist. |
| M6759 | GR 113808 | GR 113808 is a potent, selective 5-HT 4 antagonist. |
| M6343 | 4F 4PP oxalate | 4F 4PP oxalate is a selective 5-HT 2A antagonist. |
| M6333 | 3-AQC | 3-AQC is a 5-HT 3 antagonist. |
| M6065 | Ziprasidone HCl monohydrate | Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. |
| M6064 | Ziprasidone HCl | Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder. |
| M6058 | Vortioxetine | Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. |
| M6051 | Venlafaxine | Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. |
| M6050 | Venlafaxine HCl | Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia. |
| M6027 | Trazodone hydrochloride | Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. |
| M5992 | Tegaserod maleate | Tegaserod maleate is a partial agonist of the 5-HT4 receptor. Tegaserod maleate stimulates the peristaltic reflex and accelerates gastrointestinal transit. |
| M5989 | Tandospirone | Tandospirone (SM-3997) is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). |
| M5956 | Sertindole | Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. |
| M5951 | Sarpogrelate HCl | Sarpogrelate (MCI-9042) hydrochloride, a selective 5-HT2 antagonist, with pKis of 8.52, 6.57, and 7.43 for 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. |
| M5938 | Rizatriptan Benzoate | Rizatriptan Benzoate is an agonist at serotonin 5-HT1B and 5-HT1D receptors. Rizatriptan blocks neurogenic vasodilation via an action on 5-HT(1D) receptors located on perivascular trigeminal nerves to inhibit CGRP release in anaesthetized guinea-pigs. |
| M5935 | Risperidone | Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. |
| M5920 | Ramosetron HCl | Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. |
| M5884 | Pizotifen | Pizotifen (Pizotyline) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. |
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