| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M3006 | Sertraline hydrochloride | Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM. |
| M7684 | Clozapine N-oxide | Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC. |
| M59061 | PF-03382792 | PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. |
| M3772 | SB242084 | SB242084 has a high affinity (pKi 9.0) for the cloned human 5-HT2C receptor and 100- and 158-fold selectivity over the closely related cloned human 5-HT2B and 5-HT2A subtypes respectively. |
| M54777 | Gentisein | Gentisein (NSC-329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM. |
| M54692 | MM120 | MM120 is a synthetic tryptamine that is also a partial agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor. It can be used in studies related to GAD and attention deficit hyperactivity disorder (ADHD). |
| M54596 | SB 258741 hydrochloride | SB 258741 hydrochloride is a specific 5-HT7 receptor antagonist for schizophrenia. |
| M54595 | 5-HT1A antagonist 1 | 5-HT1A antagonist 1 is a potent and selective 5-HT1A receptor antagonist with a Ki value of 35 nM.5-HT1A antagonist 1 can be used in the study of central nervous system disorders. |
| M54513 | Nemifitide diTFA | Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. |
| M53845 | 4-Chloro-L-phenylalanine | 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. |
| M53286 | CART(62-76)(human, rat) | CART(62-76)(human,rat) is a neuropeptide (62-76 residues of the CART peptide) with neurotransmitter-like effects. |
| M49944 | GM2505 | GM2505 is a novel 5-HT2A receptor agonist for studies related to treatment-refractory depression (TRD) and depressive disorder (MDD). |
| M49454 | Gepirone Hydrochloride | Gepirone Hydrochloride is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease. |
| M49351 | AX-1602 | AX-1602 is a 5-HT1A receptor antagonist, adrenergic receptor ADRA2 agonist, and cannabinoid receptor CB1 antagonist for studies related to atopic dermatitis, psoriasis, and vitiligo. |
| M41755 | MRS7925 | MRS7925 is a 5-HT2BR antagonist (Ki: 17 nM). |
| M41754 | 5-HT6 agonist 1 | 5-HT6 agonist 1 is a 5-HT6 agonist (Ki: 5 nM). |
| M41753 | NAN-190 | NAN-190 is a serotonin receptor 5-HT antagonist. |
| M41752 | PNU109291 | PNU109291 is a potent and selective 5-HT1D agonist. |
| M41751 | GSK215083 | GSK215083 is a high affinity 5-HT6 receptor antagonist. |
| M41750 | 5-HT3 antagonist 4 | 5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. |
| M41749 | GR 55562 hydrochloride | GR 55562 hydrochloride is a selective 5-HT1B receptor antagonist. |
| M41748 | 5-HT6R antagonist 1 | 5-HT6R antagonist 1 is a 5-HT6R antagonist (Ki: 5 nM). |
| M41747 | GR 55562 dihydrochloride | GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. |
| M41746 | JPC0323 | JPC0323 is a dual 5-HT2C/5-HT2A receptor positive allosteric modulator. |
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