| Cat.No. | Name | Information |
|---|---|---|
| M5219 | AEBSF HCl | AEBSF HCl is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. |
| M3651 | Aprotinin | Aprotinin is a small protein serine protease inhibitor which is used to reduce perioperative blood loss and transfusion. |
| M2952 | PMSF | PMSF is an irreversible serine/cysteine protease inhibitor. PMSF is commonly used in the preparation of cell lysates. |
| M59168 | L-Tyrosine 7-amido-4-methylcoumarin | L-Tyrosine 7-amido-4-methylcoumarin (H-Tyr-AMC) is a synthetic substrate that is used in the study of serine proteases. It is reversibly bound to Sephadex G-100 and is hydrolyzed by protease enzymes in an acidic environment, generating an AMC chromatographic peak. This product has been shown to inhibit serine protease activity and, when incubated with the enzyme, reduces the hydrolysis of synthetic substrates. Synthetic H-Tyr-AMC can be used to study the inhibition of serine proteases by various inhibitors and their binding sites on the enzyme. |
| M58455 | VRK-IN-1 | VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC50 of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders. |
| M52523 | Urinary Trypsin Inhibitor Fragment | Urinary Trypsin Inhibitor Fragment is a fragment derived from urinary trypsin inhibitor by proteolysis. |
| M52519 | Chymotrypsinogen | Chymotrypsinogen is an inactive precursor of Chymotrypsin. |
| M52517 | Enteropeptidase | Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. |
| M40518 | Ulinastatin | Ulinastatin Ulinastatin is an inhibitor of serine protease and urinary trypsin with anti-inflammatory activity and is used in studies related to pancreatitis, sepsis and septic shock. |
| M30043 | TPCK | TPCK (L-1-Tosylamido-2-phenylethyl chloromethyl ketone; L-TPCK) is a potent serine protease inhibitor that reacts with the retinoblastoma protein (RB)-binding core of HPV-18 E7 protein and abolish its RB-binding capability. TPCK is able to modify E7 protein in live keratinocytes following its addition to the culture medium. |
| M21530 | Sebetralstat | Sebetralstat is an orally active plasma kininase (KLKB1) inhibitor for studies related to hereditary angioedema (HAE). |
| M21037 | HPK1-IN-2 | HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity. |
| M20773 | BioE-1115 | BioE-1115 is a highly selective and potent dual inhibitor of PAS kinase (PASK) and casein kinase 2α (CK2α) with IC50 of ~4 nM and ~10 μM, respectively. |
| M14534 | WNK-IN-11 | WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1. |
| M14532 | Avoralstat | Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research. |
| M11505 | 7-Amino-4-methylcoumarin | 7-amino-4-methylcoumarin (Coumarin 120) is used as a fluorescent probe for many serine proteases. Used for high performance liquid chromatographic labeling. |
| M11406 | Berotralstat | Berotralstat (BCX7353) was a second generation plasma kallikrein inhibitor with low toxicity and high specificity, and was used for the diagnosis of hereditary angioedema (HAE). Berotralstat works by blocking the enzyme activity of plasma Kallikrein that releases bradykinin, a major biological peptide that promotes swelling and pain associated with HAE attacks. |
| M11214 | WNK463 | WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively. |
| M10641 | FOY-251 mesylate | FOY-251 mesylate is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies. |
| M9648 | Empesertib | Empesertib (BAY1161909) is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase (IC50 of < 1 nM), with potential antineoplastic activity. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
