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Parasite Antiparasitics

Cat.No.  Name Information
M3209 Oxfendazole Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
M41210 Carpaine Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity.
M5421 Artemotil Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys.
M5419 Antimonyl potassium tartrate trihydrate Antimony potassium tartrate trihydrate is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis.
M5132 Quinacrine Dihydrochloride Dihydrate Quinacrine Hydrochloride Hydrate (Mepacrine Hydrochloride) is an antimalarial that has anti-tumor effects in vivo and in vitro. Quinacrine hydrochloride hydrate inhibits NF-κB, activates p53 signal transduction and induces apoptosis in tumor cells.
M5021 Dinotefuran Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
M4991 Dihydroartemisinin Dihydroartemisinin is a potent anti-malaria agent. Dihydroartemisinin, a derivative of artemisinin in which the C-10 lactone group is replaced by hemiacetals and active metabolites of all artemisinin compounds, is a widely used antimalarial compound that effectively induces iron death in acute myeloid leukemia cells (HL60, KG1, and THP-1) by regulating iron metabolism.
M4910 Secnidazole Secnidazole (flagellate) is a nitroimidazoles anti - infective compound.
M4892 GNF179 GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2).
M4886 Selamectin Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM.
M4669 Tuberostemonine Tuberostemonine is an alkaloid, an antimalarial that targets plasmodium falciparum ferridogen-NADP + reductase (pfFNR).
M4645 Filixic-acid-ABA Filixic-acid-ABA
M4583 (-)-Maackiain Maackiain (DL-Maackiain) was separated from Maackia amurensis Rupr. Et Maxim. Maackiain (DL-Maackiain) is a larval insecticide against Aedes aegypti with a LD50 of 21.95 μg/ mL. Maackiain (DL-Maackiain) induces DNA fragmentation into oligonucleosome size fragments, similar to apoptotic characteristics such as HL-60 cells.
M4425 3-Butylidenephthalide 3-butylidenephthalide (i.e. 3-butylidenephthalide) is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort. It has insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera Litura Spodoptera).
M4285 Harpgide Harpgide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL.
M3990 Betulonic acid Betulinic acid (Betulinic acid) is an inhibitor of eukaryotic cell topoisomerase I with IC50 value of 5 μM. It has anti-inflammatory, anti-malaria, anti-AIDS and anti-tumor activities. Betulinic acid is also a new nF-KB agonist.
M3604 Sulfadoxine Sulfadoxine is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
M3441 Clorsulon Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep.
M3245 Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC5 of about 0.01 μg/ml
M3081 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
M3061 Tetramisole hydrochloride Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
M2986 Ronidazole Ronidazole is an antiprotozoal agent.




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