| Cat.No. | Name | Information |
|---|---|---|
| M10064 | Uridine 5'-diphosphoglucose disodium salt | Uridine 5'-diphosphoglucose disodium salt is an agonist of the P2Y14 receptor, with EC50 of 0.35 μM. Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM. |
| M5986 | Suramin sodium salt | Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases). |
| M3280 | Clopidogrel | Clopidogrel is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. |
| M3069 | Ticagrelor | Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM respectively. |
| M2234 | Prasugrel | Prasugrel is a platelet inhibitor irreversibly binding to P2Y12 receptors. |
| M58647 | BzATP triethylammonium | BzATP triethylammonium salt acts as a P2X receptor agonist with pEC50s of 8.74, 5.26, 7.10, 7.50, 6.19, 6.31, 5.33 for P2X1, P2X2, P2X3, P2X2/3, P2X4 and P2X7, respectively. |
| M56546 | NF449 octasodium | NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. |
| M56302 | 2-Thio-UTP tetrasodium | 2-Thio-UTP tetrasodium is a potent P2Y2, P2Y4 and P2Y6 agonist, which an be used for the research of cancer. |
| M55230 | UDP-Galactose disodium | UDP-Galactose disodium is a monosaccharide and a P2Y14 receptor agonist with an EC50 value of 0.67 μM. |
| M38965 | N6-(4-Hydroxybenzyl)adenosine | N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). |
| M30139 | 2-Methylthioadenosine diphosphate trisodium | 2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. |
| M28720 | JNJ-54175446 | JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. |
| M25580 | PPTN hydrochloride | PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. |
| M25420 | Camlipixant | Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. |
| M14245 | A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. |
| M14041 | Diquafosol tetrasodium | Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease. |
| M11483 | A 438079 | A 438079 is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11482 | A 438079 hydrochloride | A 438079 Hydrochloride is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11206 | A-317491 | A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM). |
| M10915 | RO3 | RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor |
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