| Cat.No. | Name | Information |
|---|---|---|
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7791 | Exo-1 | Exo1 is a reversible inhibitor of exocytosis, also a Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator. |
| M21339 | 2-(Chloromethyl)benzoic acid | 2-Chloromethylbenzoic Acid acts as a reagent for the synthesis of (azolyl)methyl)arylbenzamides as dual inhibitors of VEGFR-1/2 kinases. |
| M21333 | 11-Mercaptoundecanoic acid | 11-Mercaptoundecanoic acid (MUA), a thiol-containing fatty acid used to design monolayers, has been used to prepare self-assembled monolayers (SAMs), hybrid monolayers, and metal-conjugated nanoparticles. |
| M21302 | Narasin | Narasin is a cationic ion carrier and anticoccidial agent. narasin inhibits NF-κB signaling and induces apoptosis (tumor cell death), it has activity against gram-positive bacteria, anaerobic bacteria, mycoplasma and coccidia, and it also has antiviral effects. |
| M21208 | BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. |
| M21163 | Decapeptide-12 | Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with the C-terminal residue of tyrosinase (Kd: 61.1 μM). decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 µM ). Sequence: YRSRKYSSWY. |
| M21152 | SJ6986 | SJ6986 is a potent, selective, and orally effective GSPT1/2 degradation agent with a DC50 value of 2.1 nM (Dmax 99%) for GSPT1. |
| M21133 | VT107 | The pan-TEAD transcription factor inhibitor VT-104 binds to a lipid pocket on TEAD, preventing its auto-palmitoylation, similar to the previously highlighted TEAD inhibitors. |
| M21103 | Iclepertin | Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS). |
| M21077 | BMS-986176 | BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies. |
| M21073 | 4-Deoxypyridoxine hydrochloride | 4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities. |
| M21046 | Bakkenolide A | Bakkenolide A, extracted from Petasites tricholobus, has been suggested to against cancer and display protective effects on inflammatory cytokines formation. |
| M21044 | DL-Serine | DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV). |
| M21017 | Sugammadex sodium | Sugammadex sodium is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults. |
| M21016 | Scyllo-Inositol | Scyllo-Inositol is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm. |
| M21013 | Clodronate disodium tetrahydrate | Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. |
| M21010 | L-Carnosine | L-Carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress. |
| M21009 | L-Ornithine hydrochloride | L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. |
| M21007 | Phytic acid | Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. |
| M21006 | Citicoline sodium | Citicoline is an essential intermediate in the synthesis of the major phospholipid of the cell membranes, phosphatidylcholine (PtdCho). It increases plasma adrenocorticotropic hormone (ACTH) levels and potentiates serum thyrotrophin (TSH) levels by activating the central cholinergic system. |
| M21005 | Dipivefrin Hydrochloride | Dipivefrin (Dipivefrine, Propine, Pivalephrine) is a prodrug of epinephrine which is hydrolyzed to epinephrine after absorption into the eye. |
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