| Cat.No. | Name | Information |
|---|---|---|
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7791 | Exo-1 | Exo1 is a reversible inhibitor of exocytosis, also a Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator. |
| M10962 | RU 59063 | RU 59063 is a prototype of high-affinity nonsteroidal androgen receptor (AR) ligands. |
| M10950 | SPD304 | SPD304 is a selective inhibitor of tumor necrosis factor α (TNF-α) that promotes the separation of tumor necrosis factor trimers, thereby blocking their interaction with receptors. SPD304 inhibits tumor necrosis factor in vitro α and receptor 1 binding IC50 The value is 22 μM. |
| M10949 | C 87 | C87 is a novel small molecule inhibitor of TNFα; Efficient inhibition of TNFα-induced cytotoxicity,IC50 The value is 8.73 μM. |
| M10947 | INT-767 | INT-767 is a farnidol X receptor (FXR)/TGR5 dual agonist,EC50 The values are 30 and 630 nM, respectively. |
| M10946 | Glyco-Obeticholic acid | Glyco-obeticholic acid is an active metabolite of taurine. Obeticholic Acid is an oral bioavailable fancy-like X receptor (FXR) agonist. |
| M10944 | BT-13 | BT-13 is a potent, glial-derived neurotrophic factor (GDNF) receptor RET selective agonist (independent of GDNF ligands) that promotes the growth of process ninsters in vitro sensory neurons and mitigates the occurrence of neuropathy in rats. |
| M10912 | asukamycin | |
| M10911 | ZXH-3-26 | ZXH-3-26 is a PROTAC connected by the Cereblon ligand and brd4 ligands, and after 5 hours of processing,DC50 Approximately 5 nM. |
| M10901 | viloxazine | |
| M10895 | Umirolimus | Umirolimus, a derivative of macrotriene lactone Rapamycin, is a powerful immunosuppressant and anti-inflammatory agent. Umirolimus is highly lipophilic and can be used as a drug-eluting stent. |
| M10893 | Tesetaxel | |
| M10891 | Taranabant | Taranabant is a potent and selective cannabinoid 1 (CB1) receptor reverse agonist that inhibits binding and the functional activity of multiple agonists, acting on human CB1R,Ki 0.13 nM. |
| M10889 | SHP836 | SHP836 is an allosteric inhibitor of SHP2 that inhibits SHP2 IC50 The value is 12 μM. |
| M10888 | SHP394 | SHP394 is a potent, orally active, allosterical selective SHP2 inhibitor,IC50 23 nM. |
| M10887 | SHP389 | SHP389 is an allosteric inhibitor of SHP2, which is anti-SHP2 and p-ERK IC50 The values are all 36 nM. |
| M10882 | RMC-0331 | RMC-0331 (RM-023) is a highly potent, selective, and oral bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation by disrupting RAS-SOS1 interactions. |
| M10878 | Reldesemtiv | Reldesemtiv (CK-2127107) is a selective, orally active next-generation rapid skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates rapid skeletal muscle fibrils, EC50Is 3.4 μM. |
| M10877 | QCA570 | QCA570 is made up of Cereblon ligands and BET ligands connected to PROTAC, which is paired with the BRD4 BD1 protein IC50 The value is 10 nM. |
| M10874 | plocabulin | Pm-060184 is a microtubulin polymerization inhibitor. |
| M10872 | Lufotrelvir | PF-07304814 IS A PHOSPHATE PRODRUG FOR PF-00835231 THAT BINDS AND INHIBITS SARS-CoV-2 3CLpro Active, Ki is 174 nM. |
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