| Cat.No. | Name | Information |
|---|---|---|
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7791 | Exo-1 | Exo1 is a reversible inhibitor of exocytosis, also a Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator. |
| M11288 | NCGC00229600 | NCGC00229600 is an allosteric reverse agonist of TSHR. NCGC00229600 inhibits TSH and stimulates antibody activation of internally expressed TSHRs in Graves' disease. |
| M11285 | HWL-088 | Hwl-088 is a highly effective, orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 18.9 nM) with moderate PPARδ activity (EC50 570.9 nM). Hwl-088 improves glucose and lipid metabolism. |
| M11284 | Cetaben | Cetaben is a PPARα -independent peroxisome proliferator that can effectively reduce cholesterol and triglyceride concentrations. |
| M11279 | GNE-6468 | Gne-6468 is a potent and selective RORγ (RORc) reverse agonist with an EC50 value of 2 nM. Gne-6468 inhibited IL-17 in PBMC with EC50 value of 30 nM. |
| M11276 | SCO-267 | SCO-267 is a full agonist of the GPCR GPR40, whose activation stimulates secretions of insulin and incretin. |
| M11275 | PSB-12379 | Psb-12379 is a nucleotide analogue and a potent ECTO-5 '-nucleotidase (CD73) inhibitor with Kis values of 9.03 nM (rat) and 2.21 nM (human). |
| M11274 | Lufenuron | Lufenuron is a bioactive chemical. |
| M11273 | UNC5293 | UNC5293 is a potent and selective inhibitor of MERTK (Ki=190 pM). UNC5293 inhibits MERTK (IC50=0.9 nM) and is more selective for Axl, Tyro3 and Flt3. UNC5293 showed excellent pharmacokinetic properties in mice. |
| M11174 | Mefentrifluconazole | Mefentrifluconazole, a new azole derivative, is a broad-spectrum antifungal agent. Mefentrifluconazole is a highly selective and orally active fungal CYP51 inhibitor (Kd= 0.5 nM). |
| M11173 | PC945 | PC945 is a potent antifungal triazole drug that is resistant to a variety of sensitive and resistant strains of Aspergillus fumigatus. PC945 is a potent, tightly bound inhibitor of aspergilloxine 14α-demethylase (CYP51A/CYP51B) activity.IC50s are 0.23 μM and 0.22 μM, respectively. |
| M11138 | 7beta-Hydroxybufalin | 7beta-Hydroxybufalin is a natural product. |
| M11135 | DELPHINIDIN-3-O-GALACTOSIDE | Delphinidin-3-O-galactoside chloride has anti-obesity and hypolipidemic effects. Delphinidin-3-O-galactoside (D3G) is a water-soluble anthocyanin with antioxidant activity. D3G is capable of masking the EGCG-induced cytotoxicity and ER stress, presumably through up-regulation of antioxidant enzymes and heat shock proteins. |
| M11123 | Brevicornin | Brevicornin is a flavonol compound isolated from Epimedium. |
| M11121 | Dehydrobufotenine | |
| M11112 | Tarasaponin IV | Tarasaponin IV is a zymbrane-type triterpene saponin isolated from the bark of the tree. Tarasaponin IV can be used in cancer research. |
| M11054 | Norgestrel | Norgestrel, a synthetic analogue of progesterone, is a powerful neuroprotective antioxidant that prevents photoinduced ROS production and cell death in photosensitive cells. |
| M11043 | DJ001 | DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase-σ (PTPσ) inhibitor,IC50 is 1.43 μM. DJ001 has no inhibitory activity against other phosphatases and only moderate inhibitory activity against protein phosphatase 5. DJ001 Promotes hematopoietic stem cell regeneration. |
| M11042 | ASK1-IN-2 | ASK1-IN-2 is a potent, orally active apoptosis signal-modulating kinase 1 (ASK1) inhibitor,IC50 The value is 32.8 nM. |
| M11035 | L-Perillaldehyde | |
| M11004 | GSK-2324 | GSK2324 is a FXR agonist with EC50 value of 50 nM. |
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