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Microtubule Microtubule

Cat.No.  Name Information
M1970 Paclitaxel Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM.
M3912 Vinblastine sulfate Vinblastine sulfate is an anti-mitotic agent which arrests the cell cycle in the G2/M-phase.
M1940 Docetaxel Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity.
M10844 Laulimalide Laulimalide is an Microtubule stabilizing agent. Laulimalide is a potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used).
M3550 Vinorelbine Vinorelbine is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.




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