| Cat.No. | Name | Information |
|---|---|---|
| M2767 | Ifenprodil Tartrate | Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. |
| M9566 | Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate. |
| M2884 | NMDA | NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. |
| M3003 | CB-839 | Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. |
| M42206 | GluN2B-NMDAR antagonist-1 | GluN2B-NMDAR antagonist-1 is an orally active GluN2B-NMDAR antagonist. |
| M42205 | Risevistinel | Risevistinel (NYX-783) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. |
| M42204 | NMDA receptor antagonist 6 | NMDA receptor antagonist 6 is an antagonist of NMDA receptor, targeting to the glycine binding site. |
| M42203 | CP-465022 | CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. |
| M42202 | Nevadistinel | Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. |
| M42201 | NMDA receptor antagonist 7 | NMDA receptor antagonist 7 is GluN2B subunit-selective NMDA Receptor antagonist, with an Ki of 93 nM and an IC50 of 72 nM. |
| M42200 | NMDA receptor antagonist 8 | NMDA receptor antagonist 8 is GluN2B subunit-selective NMDA Receptor antagonist, with an Ki of 265 nM and an IC50 of 62 nM. |
| M42199 | DQP-26 | DQP-26 is a potent NMDAR negative allosteric modulator with IC50 values of 0.77 μM and 0.44 μM for GluN2C and GluN2D, respectively. |
| M42198 | UBP301 hydrochloride | UBP301 hydrochloride is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. |
| M42197 | AMPA receptor modulator-4 | AMPA receptor modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), is an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). |
| M41877 | Z-Cyclopentyl-AP4 | Z-Cyclopentyl-AP4 is a kainate-type glutamate receptor agonist (orthosteric agonist). |
| M41876 | CVN636 | CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC50 value of 7 nM for hu mGluR7. |
| M41875 | mGluR3 modulator-1 | mGluR3 modulator-1 is a mGluR3 modulator, with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay. |
| M41874 | LY456236 | LY456236 is a selective, non-competitive and orally active mGlu1 receptor antagonist that inhibits phosphoinositide hydrolysis with an IC50 of 0.145 μM. |
| M41873 | MK-8768 | MK-8768 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 .6nM) with excellent brain permeability. |
| M41872 | Eglumegad hydrochloride | Eglumegad (LY354740) hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. |
| M41871 | IEM-1925 bromide | IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy. |
| M31234 | Metapramine | Metapramine (19560 RP) is an antidepressant agent, inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel. |
| M30972 | Pomaglumetad methionil | Pomaglumetad methionil (LY2140023 hydrate) is an oral methionine precursor of the potent specific mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil is well-tolerated and has a distinct safety profile, and can be used for schizophrenia. |
| M30912 | Ro 25-6981 hydrochloride | Ro 25-6981 hydrochloride is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 hydrochloride shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 hydrochloride has the potential for the research of parkinson's disease (PD). |
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