Delivery vehicle / Excipient
| Cat.No. | Name | Information |
|---|---|---|
| M59145 | DOPE-PEG2000 ammonium | DOPE-PEG2000 ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate, which can be used for bioactive molecular delivery. |
| M58667 | DOPG sodium | DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. |
| M56706 | Lipid 5 | Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. |
| M49825 | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that can be used in the synthesis of phospholipid vesicles to improve protein encapsulation. |
| M49814 | NT1-014B | NT1-014B is an effective encapsulated NT1-like lipid with amphotericin B (AmB) that dopes NT-like lipids into BBB-impermeable lipid nanoparticles (LNPs), allowing the LNPs to pass through the BBB. |
| M49811 | Dimethyldioctadecylammonium bromide | Dimethyldioctadecylammonium bromide is a synthetic cationic lipid consisting of a positively charged ammonium head group and two long hydrophobic tails that can be used to form liposomes and other lipid-based nanoparticles, which are commonly used in studies related to gene delivery and vaccine development. |
| M49810 | FTT5 | FTT5 is an ionizable lipid that efficiently delivers long mRNAs in vivo. |
| M49808 | 306Oi10 | 306Oi10 is a branched ionizable liposome that can be used to construct lipid nanoparticles (LNPs) for messenger RNA delivery. |
| M49807 | TCL053 | TCL053 is an ionizable lipid that can be used to efficiently introduce active ingredients, especially nucleic acids, into cells. In addition, TCL053 is capable of forming lipid nanoparticles (LNPs) with dipalmitoylphosphatidylcholine (DPPC), polyethylene glycol dimyristoylglycerol (PEG-DMG), and cholesterol, which can be used to deliver Cas9 mRNA and sgRNA into skeletal muscle. |
| M49806 | Genevant CL1 | Genevant CL1 is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used in studies related to mRNA lipid nanoparticle (LNP) vaccine delivery. |
| M49805 | CCD Lipid01 | CCD Lipid01 is a cationic lipid that can be used to deliver bioactive agents to cells and tissues. |
| M49801 | 5A2-SC8 | 5A2-SC8 is a degradable lipid-like compound (ester-based dendrimer) that can be used for small RNA delivery. |
| M49800 | PEG2000-DSPE | PEG2000-DSPE can be used to synthesize stable nucleic acid lipid particles (SNALPs).SNALPs represent some of the earliest and best-functioning siRNA-ABC nanoparticles described. |
| M49796 | DSPE-PEG2K-NHS | DSPE-PEG2K-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes for the delivery of DNA or mRNA vaccines. |
| M49795 | ALC-0159 | ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an excipient for vaccines. |
| M49793 | DPPG sodium | DPPG sodium is a phospholipid containing long chain (16:0) palmitic acid inserted in the sn-1 and sn-2 positions.DPPG sodium can be used to prepare micelles, liposomes and other types of artificial membranes. |
| M49396 | ATX-0114 | ATX-0114 is an ionizable cationic lipid. |
| M42457 | Ionizable lipid-1 | Ionizable lipid-1 is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure. |
| M25559 | DOPS sodium | DOPS sodium is a ubstitute for Phosphoserine/phosphatidylserine. DOPS can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors, and in lipid mixtures to mimic platelet membranes for coagulation studies. |
| M22503 | A18-Iso5-2DC18 | A18-Iso5-2DC18 could not only deliver mRNA vaccines robustly but also activate the stimulator of interferon genes (STING) pathway. A18-Iso5-2DC18 is an alkylene ketone-derived. |
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