| Cat.No. | Name | Information |
|---|---|---|
| M8975 | CWHM-12 | CWHM-12 is a potent inhibitor of αV integrins with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1, respectively. |
| M9173 | Cilengitide TFA | Cilengitide TFA is a potent integrin inhibitor for αvβ3 and αvβ5 receptor with IC50 of 4.1 nM, 79 nM in cell-free assays respectively. |
| M2042 | Cilengitide | Cilengitide (EMD 121974, NSC 707544) is a selective inhibitor of αvβ3 integrin and αvβ5 integrin with IC50 of 1 nM and 140 nM, respectively. |
| M13754 | OSU-T315 | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). |
| M13752 | BIO-1211 | BIO-1211 is a highly selective and orally active α4β1 (VLA-4) inhibitor, with IC50 values of 4 nM and 2 μM for α4β1 and α4β7, respectively. |
| M53332 | Cyclo(Arg-Gly-Asp-D-Phe-Val) | Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. |
| M53331 | Cyclo(Ala-Arg-Gly-Asp-Mamb) | Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research. |
| M53330 | Eptifibatide monoacetate | Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity. |
| M53329 | cRGDfK-thioacetyl ester | cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. |
| M53328 | Lys-Gln-Ala-Gly-Asp-Val | Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. |
| M53327 | Galacto-RGD | Galacto-RGD is an RGD analogue that can be coupled with the radioactive isotope 18F and used as an integrin α₅β₃ selective tracer. |
| M53326 | RGDSPASSKP | RGDSPASSKP is a RGDS-containing fibronectin decapeptide. |
| M53325 | Batifiban | Batifiban, a cyclic peptide, is a platelet glycoprotein GPⅡb/Ⅲa antagonist, and inhibits platelet aggregation. |
| M53324 | EILEVPST | EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. |
| M53323 | LDV-FITC | LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide. |
| M53322 | REDV | REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. |
| M45159 | SGN-B6A | SGN-B6A is an integrin-targeted ADC that selectively targets solid tumors by recognizing ITGB6. |
| M45158 | Alintegimod | Alintegimod is an orally active variant activator of integrins αLβ2 and α4β1 that enhances T cell activation and adhesion. |
| M45156 | JSM-6427 | JSM-6427 is an integrin α5β1 antagonist. |
| M45155 | MORF-057 | MORF-057 is an oral small molecule α4β7 integrin (integrin) inhibitor that can be used in studies related to ulcerative colitis (UC). |
| M45154 | PN-943 | PN-943 is a potentially first-in-class, orally active, specific α4β7 integrin antagonist peptide for studies related to inflammatory bowel disease (IBD). |
| M45153 | PLN-1474 | PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis. |
| M45152 | IDL-2965 | IDL-2965 is a small molecule heterocyclic compound that is also an inhibitor of αvβ1, αvβ3 , and αvβ6 for studies related to NAFLD and idiopathic pulmonary fibrosis. |
| M41632 | α7β1 integrin modulator-1 | α7β1 integrin modulator-1 is a potent α7β1 integrin modulator. |
| M41631 | 3-Hydroxyxanthone | 3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . |
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