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HDAC Histone deacetylases

Cat.No.  Name Information
M9638 4-Phenylbutyric acid (4-PBA) 4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM.
M6176 TMP195 TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays.
M6073 WT161 WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM.
M5199 Santacruzamate A Santacruzamate A is a picomolar level selective inhibitor of HDAC2 with an IC50 of 85.8 nM, a Class I HDAC, with relatively little inhibition of HDAC4 or HDAC6, both Class II HDACs.
M4986 LMK-235 LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).
M2977 RGFP966 RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.
M2236 CI-994 CI-994 (N-acetyl dinaline, PD 123654) is a novel orally active HDAC inhibitor with IC50 of 0.57 μM for HDAC1.
M2101 PCI-34051 PCI-34051 is a potent histone deacetylase (HDAC) 8 inhibitor with IC50 of 0.01 μM.
M2014 MC1568 MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor with IC50 of 220 nM.
M2007 Romidepsin (FK228) Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended
M1791 Entinostat (MS-275) Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
M1790 MGCD0103 MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively.
M1780 Vorinostat Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M1778 SB939 SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer.
M1753 Trichostatin A Trichostatin A (TSA) is a potent and specific inhibitor of mammalian histone deacetylase (HDAC) class I/II, with an IC50 value of 1.8 nM for HDAC.
M1748 LBH589 (Panobinostat) LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M1742 Tubacin Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.
M1738 Niltubacin Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.
M55461 Valproic acid-d6 Valproic acid-d6
M49894 Ac-Arg-Gly-Lys(Ac)-AMC acetate Ac-Arg-Gly-Lys(Ac)-AMC acetate is a substrate for histone deacetylase (HDAC) and can be used in a novel fluorescent assay for HDAC activity.




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