| Cat.No. | Name | Information |
|---|---|---|
| M2347 | (+)-Bicuculline | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| M5442 | Baclofen | Baclofen is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research. |
| M5653 | Flumazenil | Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. |
| M2949 | Piracetam | Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. |
| M2555 | AWD 131-138 | AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. |
| M2439 | Bemegride | Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning. |
| M2005 | (R)-Baclofen | (R)-baclofen, a gamma-aminobutyric acid derivative and agonist at GABA-B receptors, inhibits nerve conduction in the central nervous system and can be used in studies related to spasticity. |
| M1954 | Alpidem | Alpidem is a potent antagonist of peripheral benzodiazepine receptor (PBR). |
| M1891 | SKF 89976A hydrochloride | SKF 89976A hydrochloride is a potent GABA uptake inhibitor, selective for GAT-1. |
| M56489 | β-CCB | β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [3H]flunitrazepam and ethyl (3-[3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM. |
| M56488 | TPMPA | TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). |
| M56487 | CI-966 | CI-966 is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively. |
| M56486 | NCS-382 | NCS-382 is a potent GABA receptor antagonist and also a GHBR receptor antagonist. |
| M56485 | CGS 8216 | CGS 8216, a benzodiazepine receptor antagonist, inhibits 3H-flunitrazepam (3H-FLU) binding to rat synaptosomal membranes in vitro at subnanomolar concentrations. |
| M56484 | CGP13501 | CGP13501 is a positive allosteric modulator of GABAB receptor. |
| M56483 | TPA-023B | TPA-023B is a high-affinity and orally active GABAA receptor α2/α3 subtype (Kis of 0.73 nM/2 nM) partial agonist and a α1 subtype (Ki of 1.8 nM) antagonist. |
| M56482 | CGP46381 | CGP 46381 is an orally active GABAB receptor antagonist with IC50 of 4.9 μM. |
| M56481 | CGP35348 | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only. |
| M56480 | SCH 50911 | SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. |
| M56479 | Phaclofen | Phaclofen is a selective GABAB receptor antagonist. |
| M56478 | Lorediplon | Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. |
| M56477 | Lesogaberan | Lesogaberan (AZD-3355) is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptors. |
| M56476 | 3-Methyl-GABA | 3-Methyl-GABA is a potent GABA aminotransferase activator. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
